A meta-analysis was conducted to compare the effects of feeding dairy cows conventional sorghum (CSS) or corn silages (CCS) vs. brown midrib sorghum silage (BMRSS) on dry matter intake (DMI), milk yield, and milk composition. Data from 9 published articles (1984–2015) were used to contrast CSS (7 comparisons; 104 cows) or CCS (13 comparisons; 204 cows) vs. BMRSS. Statistical analysis was performed using fixed or random effects models in R. The degree of heterogeneity was measured with I² statistic and publication bias was determined with funnel plots and Egger’s regression test. Other sources of heterogeneity of response were analyzed through meta-regression. Estimated effect size was calculated for DMI, milk yield, and milk composition. No evidence of publication bias was observed for all variables tested. DMI and milk yield had the highest (I² = 41.5 [CSS vs. BMRSS]; I² = 72.6% [CCS vs. BMRSS]) and lowest (I² = 0%) degree of heterogeneity, respectively. Compared with CSS, cows fed BMRSS tended to increase DMI (0.83 kg/d; P = 0.09), and significantly increased milk yield (1.64 kg/d; P < 0.001), milk fat (0.09%; P = 0.03), and yields of milk fat (0.08 kg/d; P < 0.001), protein (0.04 kg/d, P < 0.001), and lactose (0.16 kg/d; P = 0.02). No differences were observed for milk protein and lactose percentage (P > 0.05). Compared with CCS, cows fed BMRSS increased milk fat (0.10%; P = 0.009), but decreased milk protein (0.06%; P = 0.03). There were no effects on DMI, milk yield, yields of milk fat, protein, and lactose, and lactose percentage between CCS and BMRSS. Meta-regression indicated that days in milk affected DMI and milk production when CSS was compared with BMRSS and DMI when CCS was compared with BMRSS. Overall, lactation performance improved when cows were fed diets formulated with BMRSS compared with cows fed diets formulated with CSS; however, performance was not different between cows fed BMRSS and CCS. Future research comparing BMRSS with CSS or CCS needs to consider days in milk because cows respond differently throughout their lactation according to meta-regression analysis.