Abstract #M69

Section: Animal Health
Session: Animal Health I
Format: Poster
Day/Time: Monday 7:30 AM–9:30 AM
Location: Exhibit Hall B
# M69
Effects of Protemace on the performance and small intestinal health of Jersey calves challenged with Salmonella enterica serotype Typhimurium at 7 day of life.
Y. Liang*1, R. Hudson1, M. Ballou1, 1Department of Animal and Food Sciences, Texas Tech University, Lubbock, TX.

The objective of this study was to determine the effects of Protemace on the performance and health of Jersey calves challenged with Salmonella enterica serotype Typhimurium. Jersey bull calves within 1 d of birth were blocked by total serum protein and initial BW and randomly assigned to treatments in a 2 × 2 factorial arrangement with Protemace (PM) and Salmonella enterica (ST) as the main effects (n = 8). Calves challenged with ST were administered 5.5 × 106 cfu in the AM milk replacer on d 7. Calves supplemented with PM had 8 mL added directly to the bottle before each feeding. All calves were fed 300 g of a 22% CP and 20% fat milk replacer twice daily. Calves had ad libitum access to a starter. Blood samples and body weight measurements were taken at d 0, 7, 10, 14, and 21. All calves were harvested on d 21, and duodenum and ileum samples collected for histomorphological measurements. Data were analyzed as a repeated measures with the fixed effects of PM, ST, time, and all possible interactions; block was included as an additional random effect. There was no treatment × time difference on ADG (P = 0.802); however, ST calves tended to decrease ADG (P = 0.054). No treatment × time difference was observed in rectal temperature (P = 0.883), but ST calves had greater rectal temperature than unchallenged calves at d 9 to 12 post challenge (P < 0.001). There was no treatment × time or treatment differences in fecal dry matter percentage either before or post challenge (P0.261). There was no treatment × time difference in plasma haptoglobin concentration (P = 0.736); however, calves supplemented with PM had decreased concentrations (P = 0.016). The ST calves had a tendency (P = 0.082) for reduced villi:crypt in the duodenum, but PM calves had greater villi:crypt in the duodenum (P = 0.040). Additionally, the ST calves had a tendency (P = 0.072) for reduced villi:crypt in the ileum; however, there was no effect due to PM (P = 0.154). These data indicate that Protemace reduced some inflammation indices of Jersey calves challenged with Salmonella enterica on d 7 of life.

Key Words: calf, health, nutrition