While data surrounding the use of colostral immunoglobulins (IgG) to calves to achieve passive transfer of immunity is abundant, data supplementing calves with colostral immunoglobulins after 24 h of age is a seldom researched disease prevention strategy to reduce antibiotic use. The study objectives were to evaluate the effect of supplementing calves with a concentrated, whey-based IgG, from birth to d 14 on intake and performance. The IgG was from a commercially available colostrum replacer product (Premolac, Zinpro Corp., Eden Prairie, MN; PZ). Upon arrival at the facility, 1,037 newborn, Holstein calves were randomly assigned to 1 of 3 treatments of IgG: 1) 0 g (CON; negative control), 2) 10 g (CR10; 23 g PZ), or 3) 20 g (CR20; 46 g PZ)/d. Treatments were added to milk replacer and fed 2×/d to individually housed calves. Calf BW was recorded on d 0, 15, pre-weaning (d 53) and hutch exit (d 69). Grain intake was measured 1x/wk. All milk replacer refusals were recorded. Continuous outcomes were analyzed using the MIXED procedure of SAS (SAS Institute Inc., Cary, NC). Percentage of calves that refused milk and feeding refusal number were analyzed using the GLIMMIX procedure with a binary distribution or a Poisson distribution and log link, respectively. Supplementing IgG from PZ reduced the percentage of calves that had a milk refusal event in at least one meal during the first 3 weeks of age (38.8, 23.3 and 20.0% for CON, CR10, and CR20 respectively; P < 0.01). Among refusals, CR20 calves refused less feedings (1.5 vs. 2.1; P = 0.03) and less total milk (1.51 vs. 1.99 L; P = 0.04) compared with CON calves. Grain intake was similar among treatments (P = 0.29). Calves fed CR20 were heaviest at d 15 (43.5, 42.9 and 42.2 for CR20, CR10, and CON respectively; P < 0.01). Total gain and ADG from d 0 to 14 were greatest for CR20, intermediate for CR10, and lowest for CON calves (3.6, 3.0 and 2.2 kg and 0.24, 0.20 and 0.15 kg/d respectively; P < 0.01). Supplementing PZ, especially 20 g of IgG from PZ, d 0 to 14 improved growth and reduced milk refusals in Holstein calves.