The objective of this study was to evaluate growth and feed efficiency of dairy heifers differing in predicted genomic residual feed intake as a lactating cow (RFI) and either fed ad-libitum or limit-fed. Post-bred Holstein heifers (128, ages 14–20 mo) were blocked by BW (heavy, 516 kg; medium-heavy, 485 kg; medium-light, 457 kg; and light, 420 kg) with 32 heifers per block. Heifers within block were sorted by genomic RFI to obtain 2 pens of high and 2 pens of low RFI within each weight block (8 heifers per pen). Diet treatments were i) a control diet (CON) comprised of corn silage and alfalfa silage (59.2% TDN, 12.7% CP, and 47.8% NDF, DM basis), and ii) a diet limit-fed (LIMIT) to 90% of CON intakes (62.4% TDN, 13.4% CP, and 42.7% NDF, DM basis). The LIMIT diet contained the same forages as CON but included corn and soybean meal to obtain similar nutrient intakes as CON. Treatments were randomly allocated to obtain a 2x2 factorial arrangement and implemented within a 120-d trial. Data were evaluated using the MIXED procedure in SAS 9.4 with pen as experimental unit. Feed intake was greater (P = 01) for heifers fed CON diets (11.0 vs. 9.98 kg DM/d). Feed intake was unaffected (P > 0.34) by RFI with no interaction between diet and RFI. Protein intake was greater (P = 0.04) for heifers fed CON compared with heifers fed LIMIT (1.41 vs. 1.33 kg CP/d). Intake of dietary ME tended to be greater for CON fed heifers (P = 0.07); but intakes of NEm and NEg were similar (P > 0.28) between diets. The ADG of heifers was affected by diet (P < 0.01) with CON fed heifers having greater ADG than LIMIT (0.88 vs 0.80 kg/d) potentially due to greater digesta fill for CON. The ADG of heifers was also affected (P < 0.01) by RFI with Low RFI heifers gaining more than High RFI heifers (0.86 vs. 0.83 kg/d). Feed efficiency of heifers was unaffected by diet (P = 0.70), but was improved (P = 0.01) in Low RFI heifers compared with High RFI heifers (12.1 vs. 12.8 kg DM/kg gain). Body condition gain was unaffected by RFI or diet (P > 0.36). Overall, heifers with Low genomic RFI had improved feed and growth efficiency whether fed ad-libitum or limit-fed diets.