Dale Bauman’s journey toward defining and delineating homeorhesis and the concepts around control of nutrient partitioning began with his doctoral studies at the University of Illinois on the genetic differences in the ATP citrate lyase pathway between ruminants and non-ruminants. He was the first to demonstrate the glucose sparing mechanism ruminants evolved to reduce the flow of glucose carbons into fatty acid synthesis sparing glucose for lactose synthesis. As a new assistant professor at the University of Illinois, he and his graduate students produced classic publications on the metabolic adaptations required for onset and maintenance of lactation in ruminant and non-ruminant animals. This work stimulated his thinking on how these metabolic adaptations were coordinated. His work at the University of Illinois also included the role of prolactin in the initiation of lactation in cattle. He continued his work on the biology of prolactin and somatotropin while on sabbatical leave with Allen Tucker at Michigan State University where he began thinking of the role of these hormones in coordinating metabolism with onset of lactation. Subsequently, he moved to Cornell University where he fully developed the concept of homeorhesis and published the complete concept with Bruce Currie; their much cited paper on this subject was published in 1980. Dale went on to demonstrate how homeorhetic regulation was involved in widely varying physiological states including hibernation, pregnancy, starvation, stress, lactation and growth to name a few. In the late 70s recombinant bovine somatotropin became available and Dale worked with multiple forms of this molecule both native and recombinant to study somatotropin as a key homeorhetic regulator. He and his students and colleagues published hundreds of papers, abstracts and reviews over the next quarter century. For these and other contributions to science, Dale was nominated to the National Academy of Science in 1988.